orgentec公司抗突變型瓜氨酸波形蛋白抗體酶聯免疫法試劑

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ORGENTEC公司成立於(yu) 1988年，公司總部位於(yu) 德國的美因茨市。主要產(chan) 品包括ABC試劑盒，各種標記二抗，Western試劑盒，蛋白分子量Marker，核抽提物等。ORGENTEC致力為(wei) 免疫檢測用戶提供更多的產(chan) 品與(yu) 服務。

Anti-MCV?

The Anti-MCV? ELISA by ORGENTEC detects autoantibodies against mutated citrullinated vimentin (MCV) and is an efficient and reliable serological test for rheumatoid arthritis. Anti-MCV? detects the disease at a very early stage, even in patients who test negative for rheumatoid factor, and to some degree even before the appearance of specific clinical symptoms.

Autoantibodies against mutated citrullinated vimentin are highly specific and extremely sensitive markers for rheumatoid arthritis (specificity 97 %, sensitivity > 82 %). Anti-MCV? autoantibodies are an indicator of advanced injury to the joints and aggressive progression of the disease. In contrast to the detection of antibodies against synthetic cyclic citrullinated peptides, changes in the anti-MCV concentration correspond to changes of clinical parameters. As well as allowing for an unambiguous diagnosis, the Anti-MCV? ELISA thus also makes it possible to monitor therapeutic progress.

For point-of-care diagnosis, rheumachec? provides a rapid blood test that detects both anti-MCV autoantibodies and rheumatoid factor.

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